Diagnosis of EGE requires three criteria, namely: (1) presence of GI symptoms; (2) histologic evidence of eosinophilic infiltration in one or more areas of the GI tract; and (3) exclusion of other causes of tissue eosinophilia
Algorithm for eosinophilic gastroenteritis diagnosis. 1Histologic ascertainment for absence of malignant cells or findings suggestive of IBD, connective tissue diseases or vasculitis. AEC: Absolute eosinophilic count; ANA: Anti-nuclear antibody; ANCA: Anti-neutrophil cytoplasmic antibodies; EC: Eosinophilic count; EUS: Endoscopic ultrasound; Hx: History; IBD: Inflammatory bowel disease; PE: Physical examination; S/A: Stool analysis; US: Ultrasound; EGE: Eosinophilic gastroenteritis.
Reference:
Abou Rached A, El Hajj W. Eosinophilic gastroenteritis: Approach to diagnosis and management. World J Gastrointest Pharmacol Ther. 2016 Nov 6;7(4):513-523. doi: 10.4292/wjgpt.v7.i4.513. PMID: 27867684; PMCID: PMC5095570.
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