What are the histological criteria for the diagnosis of eosinophilic gastrointestinal disease?
The diagnosis of mucosal EGIDs is established by the presence of higher than expected numbers of eosinophils on microscopic examination of gastrointestinal tract biopsies.
There are no established criteria, but the following cutoff points for the number of eosinophils per CGA (eosinophils per high power field x 400 (Eo CGA)) have been suggested:
Stomach: ≥30 eosinophils per CGA in 5 CGAs
Duodenum: ≥52 eosinophils according to CGA
Ileum: >56 for CGA in ileum
Right colon: >100 for CGA
Transverse and descending colon: >84 for CGA
Rectosigmoid colon: >64 for CGA