What are the laboratory findings in the presence of eosinophilic gastrointestinal disease?
Peripheral eosinophil counts are usually elevated in patients but may be normal in about 20% of patients.
Mucosal and serous EGIDs are characterized by higher eosinophil counts than disease involving the muscle layer.
Patients with malabsorption due to mucosal EGIDs may have an abnormal D-xylose test due to carbohydrate malabsorption and increased faecal fat excretion with prolonged prothrombin time.
Increased mucosal permeability can cause protein-losing enteropathy and subsequent hypoalbuminemia.
Anemia can result from poor iron absorption and occult gastrointestinal bleeding.
Non-EoE EGID is often associated with iron deficiency.
Serum IgE levels can be elevated, especially in children.