Hypereosinophilic syndrome:
Hypereosinophilic syndrome (HES) is an idiopathic condition associated with marked peripheral eosinophilia and can rarely present with predominant gastrointestinal symptoms.
Many patients with EGIDs can meet the diagnostic criteria for HES (absolute eosinophil count ≥1500 cells/mL present for more than six months). However, unlike EGIDs, HES involves multiple organ systems (e.g., heart, lungs, brain, and kidneys).